Playing old games with different resolutions sometimes messes up my desktop layout.
In my desktop I have MY icons disposition, such as games shortcuts on right, "temp" files in the bottom etc... and sometimes after a game session, when I return to the desktop, the icons are all mixed up or grouped to the left.
If you have this problem, download and install for your Windows version the tool Desktop Restore:
I experienced some problem with Fraps in games like Grim Fandango: it's impossible to capture a screenshot.
So I downloaded this software, ShareX, the successor of Zscreen and put CTRL+PrintScreen to take screenshots.
With the only PrintScreen or Fn(eg: F11) nothing happened playing Grim Fandango, I suppose some "hotkey" problem, but now works like a charm.
ShareX saves and uploads images by default, so set your config.